Closure of a large lumbosacral myelomeningocele post operative defect with a human cadaveric split-thickness skin graft: a case report

Spina bifida is the most common birth defect of central nervous system that compatible with life, and myelomeningocele represents its frequent form. Congenital (CMM) has a worldwide incidence 0.5 to 0.8 per 1,000 live newborns. CMM complex condition resulting from incomplete closure neural tube, mainly in lumbosacral region. The objective surgical repair reconstruction all tissue layers defect, avoiding possible postoperative complications. aim this case review present re-epithelialization patient large who primary hermetic was not because there too much tension at edges defect. Therefore, human cadaveric split-thickness skin grafts were placed over dura mater aponeurotic layer, covering entire an adequate healing completely observed eight weeks. management meningomyelocele defects major challenge no single protocol exists for reconstruction. MMC should be performed during first 72 hours after birth. After neurosurgical tube dura, requires good quality subcutaneous minimal wound stable coverage. Human are considered useful technique temporary coverage they lead more natural environment, possess ideal properties, provide physiological barrier reduces microbiological contamination, addition, it acts as bridge adhere seal beds.